HIV-1 Diversity After a Class Switch Failure
نویسندگان
چکیده
منابع مشابه
Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination
HIV-1 tat targets a variety of host cell proteins to facilitate viral transcription and disrupts host cellular immunity by inducing lymphocyte apoptosis, but whether it influences humoral immunity remains unclear. Previously, our group demonstrated that tat depresses expression of DNA-PKcs, a critical component of the non-homologous end joining pathway (NHEJ) of DNA double-strand breaks repair,...
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ژورنال
عنوان ژورنال: AIDS Research and Human Retroviruses
سال: 2010
ISSN: 0889-2229,1931-8405
DOI: 10.1089/aid.2010.0069